Physical Therapy Assistant Practice Exam

What hereditary condition results in chorea, personality disturbances, and dementia?

1. Myasthenia gravis

2. Multiple sclerosis

3. Huntington's disease

4. Guillain-Barre syndrome

The correct answer is: Huntington's disease

Huntington's disease is a hereditary condition caused by a genetic mutation in the HTT gene, leading to the production of abnormal huntingtin protein. This disease is characterized by neurological symptoms that manifest in various ways, including chorea, which refers to involuntary, erratic movements; personality disturbances, where individuals may experience changes in mood, behavior, and cognition; and dementia, which affects memory and overall cognitive function. The progressive nature of Huntington's disease means that symptoms typically worsen over time, often leading to significant challenges in daily living and requiring various therapeutic interventions. The condition is autosomal dominant, meaning that an affected individual has a 50% chance of passing the mutation to their offspring, making family history an important consideration in diagnosis and counseling. Understanding Huntington's disease and its impact is crucial for anyone involved in the care of affected individuals or studying neurological conditions.